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CD62E - IMMUNOSTEP. WE KNOW HOW

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CD62E - IMMUNOSTEP. WE KNOW HOW

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PerCP - anti Human CD62E - TEA2/1

Reference	Size	Price	Quantity	Add to cart
62EPP-100T	100 test	253,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

62EPP-100T

100 test

253,00 € tax excl.

Product Description

Clone: TEA2/1
Tested Applications: FCM
Conjugated: PerCP
Immunogen: Activated HUVEC cells
Species Reactivity: Human
Storage Buffer: PBS, 0,09% sodium Azide, may contain carrier protein-stabilizer
Regulatory Status: RUO

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Large description:

Reactivity: Reacts with the 97-115 kDa cell surface glycoprotein, E-selectin, also known as endothelial-leukocyte adhesion molecule–1 (ELAM-1). E-selectin is thought to be involved in the initial interaction of neutrophils with inflammed endothelium. CD62E is expressed on cytokine-stimulated endothelium, but in minimal amounts on unstimulated endothelium. E-selectin is heavily glycosylated. It has a calculated M.W. of 64 kDa, however, the protein runs at 107-115 kDa by SDS-PAGE.

Specificity: The antibody is specific to the human antigen E-selectin (ELAM-1, 115 kDa) that is expressed on activated endothelial cells. The ligand is expressed on neutrophils and may function as an early part in neutrophil binding to the endothelium. This antibody is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes.