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Anti-FABP6 Antibody

品牌：Antibodies

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规格：100µl

货期：

应用：

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Anti-FABP6 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-FABP6 Antibody See all FABP6 primary antibodies
Description:	Rabbit polyclonal antibody to FABP6
Specificity:	The antibody detects endogenous levels of total FABP6 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Full length fusion protein
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.1mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity).
Tissue Specificity:	Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level).
Sequence Similarities:	Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Cellular locations:	Cytoplasm. Membrane.
Database Links:	Entrez Gene: 2172?Human Entrez Gene: 16204?Mouse Omim: 600422?Human SwissProt: P51161?Human SwissProt: P51162?Mouse Unigene: 519719?Human Unigene: 142716?Mouse
Synonyms:	FABP6 Antibody FABP6_HUMAN Antibody Fatty acid binding protein 6, ileal (gastrotropin) Antibody Fatty acid-binding protein 6 Antibody Gastrotropin Antibody GT Antibody I 15P Antibody I BABP Antibody I BALB Antibody I BAP Antibody I-15P Antibody I-BABP Antibody I15P Antibody IBABP Antibody IBALB Antibody IBAP Antibody ILBP Antibody ILBP3 Antibody Ileal lipid binding protein Antibody Ileal lipid-binding protein Antibody ILLBP Antibody Intestinal 15 kDa protein Antibody Intestinal bile acid binding protein Antibody Intestinal bile acid-binding protein Antibody
Information:	Target information shown above is from the UniProt Consortium.