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Anti-F-box only protein 2 Antibody

品牌：Antibodies

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规格：100µl

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Anti-F-box only protein 2 Antibody

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Name:	Anti-F-box only protein 2 Antibody See all F-box only protein 2 primary antibodies
Description:	Rabbit polyclonal antibody to F-box only protein 2
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide contain a sequence corresponding to a region within amino acids 234 and 296 of F-box only protein 2
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 1XPBS, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Function:	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).
Cellular locations:	Cytoplasm. Microsome membrane.
Database Links:	Entrez Gene: 26232?Human Omim: 607112?Human SwissProt: Q9UK22?Human Unigene: 132753?Human Unigene: 556006?Human
Synonyms:	F box gene 1 Antibody F box only protein 2 Antibody F box protein 2 Antibody F box protein only 2 Antibody F-box only protein 2 Antibody FBG 1 Antibody FBG1 Antibody Fbs 1 Antibody Fbs1 Antibody Fbs2 Antibody FBX 2 Antibody FBX2 Antibody FBX2_HUMAN Antibody FBXO 2 Antibody FBXO2 Antibody Neural F box protein NFB42 Antibody Neural F-box protein, 42-KD, rat, homolog of Antibody NFB 42 Antibody NFB42 Antibody OCP1 Antibody organ of Corti protein 1 Antibody Prpl4 Antibody
Information:	Target information shown above is from the UniProt Consortium.