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Anti-ELOVL6 Antibody

品牌：Antibodies

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规格：100µl

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Anti-ELOVL6 Antibody

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Overview

Name:	Anti-ELOVL6 Antibody See all ELOVL6 primary antibodies
Description:	Rabbit polyclonal antibody to ELOVL6
Specificity:	The antibody detects endogenous levels of total ELOVL6 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human ELOVL fatty acid elongase 6
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	2.4mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Tissue Specificity:	Ubiquitous.
Sequence Similarities:	Belongs to the ELO family. ELOVL6 subfamily.
Post-Translational Modification:	N-Glycosylated.
Cellular locations:	Endoplasmic reticulum membrane.
Database Links:	Entrez Gene: 79071?Human Entrez Gene: 170439?Mouse Omim: 611546?Human SwissProt: Q9H5J4?Human SwissProt: Q920L5?Mouse Unigene: 412939?Human Unigene: 314113?Mouse
Synonyms:	3-keto acyl-CoA synthase ELOVL6 Antibody Elongation of very long chain fatty acids protein 6 Antibody ELOV6_HUMAN Antibody ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3 like, yeast) Antibody ELOVL fatty acid elongase 6 Antibody ELOVL6 Antibody FACE Antibody FAE Antibody Fatty acid elongase 2 Antibody Fatty acyl CoA elongase Antibody Fatty acyl-CoA elongase Antibody FLJ23378 Antibody hELO2 Antibody LCE Antibody Long chain fatty acyl elongase Antibody Long-chain fatty-acyl elongase Antibody MGC5487 Antibody Myelin associated SUR4 protein Antibody
Information:	Target information shown above is from the UniProt Consortium.