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Anti-CLCN4 Antibody

品牌：Antibodies

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规格：50µl

货期：

应用：

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Anti-CLCN4 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-CLCN4 Antibody See all CLCN4 primary antibodies
Description:	Rabbit polyclonal antibody to CLCN4
Specificity:	The antibody detects endogenous levels of total CLCN4 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from internal of human CLCN4.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons.
Tissue Specificity:	Abundant in skeletal muscle and also detectable in brain and heart.
Involvement in Disease:	Mental retardation, X-linked 49: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations.
Sequence Similarities:	Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily.
Cellular locations:	Early endosome membrane. Late endosome membrane. Endoplasmic reticulum membrane.
Database Links:	Entrez Gene: 1183?Human Entrez Gene: 12727?Mouse Entrez Gene: 60586?Rat Omim: 302910?Human SwissProt: P51793?Human SwissProt: Q61418?Mouse SwissProt: P51794?Rat Unigene: 495674?Human Unigene: 297883?Mouse Unigene: 488576?Mouse Unigene: 44406?Rat
Synonyms:	Chloride channel 4 Antibody Chloride channel protein 4 Antibody Chloride channel, voltage sensitive 4 Antibody Chloride transporter ClC-4 Antibody ClC 4A Antibody ClC-4 Antibody CLC4 Antibody ClC4A Antibody CLCN4 Antibody CLCN4_HUMAN Antibody H(+)/Cl(-) exchange transporter 4 Antibody MGC163150 Antibody
Information:	Target information shown above is from the UniProt Consortium.