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Anti-CAPN5 Antibody

品牌：Antibodies

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规格：50µl

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Anti-CAPN5 Antibody

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Overview

Name:	Anti-CAPN5 Antibody See all CAPN5 primary antibodies
Description:	Rabbit polyclonal antibody to CAPN5.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human CAPN5.
Protein Length:	640
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Tissue Specificity:	Expressed in many tissues. Strong expression in the photoreceptor cells of the retina, with a punctate pattern of labeling over the nuclei and inner segments with less expression along the other segments and outer plexiform layer.
Involvement in Disease:	Vitreoretinopathy, neovascular inflammatory: An autoimmune condition of the eye that sequentially mimics uveitis, retinitis pigmentosa, and proliferative diabetic retinopathy as it progresses to complete blindness. Patients present during the second or third decade of life with posterior uveitis and reduction of the electroretinogram b-wave. They become more symptomatic when cataracts, cystoid macular edema, and disk edema diminish visual acuity during the second stage. Severe vision loss begins during the third stage when proliferative retinal neovascularization and epiretinal membranes appear. There is an ongoing pigmentary retinal degeneration and peripheral visual field loss during all stages. In the fourth stage, proliferative vitreoretinopathy causes tractional retinal detachments at the macula and vitreous base. The fifth or end-stage disease is marked by phthisis.
Sequence Similarities:	Belongs to the peptidase C2 family.
Database Links:	Entrez Gene: 726?Human Entrez Gene: 12337?Mouse Entrez Gene: 171495?Rat Omim: 602537?Human SwissProt: O15484?Human SwissProt: O08688?Mouse SwissProt: Q8R4C0?Rat Unigene: 248153?Human Unigene: 326847?Mouse Unigene: 15526?Rat
Synonyms:	ADNIV Antibody Calpain 5 Antibody Calpain htra 3 Antibody Calpain htra-3 Antibody Calpain-5 Antibody CAN5_HUMAN Antibody CAPN 5 Antibody Capn5 Antibody nCL 3 Antibody nCL-3 Antibody New calpain 3 Antibody VRNI Antibody
Information:	Target information shown above is from the UniProt Consortium.