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IgG1

Mouse

Determined by protein A or G affinity chromatography

Measured by neutraliziation of interferon in antiviral assay; ND50 on human (HeLa/EMCV) cells is ~7-21 μg/ml in the presence of 10 ng/ml of human IFN-beta.

Neutralizes human IFN-beta; does not neutralize human IFN-alpha or gamma

Phosphate-buffered saline (PBS) containing 5% trehalose prior to lyophilization

Protein A or G affinity chromatography

For retention of full activity store at -20°C or below and avoid repeated freeze/thaw cycles